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Prostate cancer: In a study published by the Journal of the National Cancer Institute, researchers used a population-based, case-controlled study to investigate the relationship between allium vegetable intake and prostate cancer. They found that men with the highest intake of allium vegetables had the lowest risk for prostate cancer.2 Esophageal and stomach cancer: Frequent intake of allium vegetables has been inversely related with the risk of esophageal and stomach cancer.3 Several survey-based human studies have demonstrated the potential protective effects of consuming alliums, as well as reports of tumor inhibition following administration of allium compounds in experimental animals. Sleep and mood: Folate, found in onions, may help with depression by preventing an excess of homocysteine from forming in the body, which can prevent blood and other nutrients from reaching the brain. Excess homocysteine interferes with the production of the feel-good hormones serotonin, dopamine, and norepinephrine, which regulate not only mood, but also sleep and appetite as well.4